Cellular Renewal Night Cream
Retinaldehyde · Bakuchiol
US Longevity Laboratories, Inc.
323-359-5210
Longevity.com.AI is the platform where US Longevity Laboratories' clinical research and Israel.com.AI's applied artificial intelligence come together — one half laboratory, one half intelligence, built to extend how long, and how well, you live.
In collaboration with US Longevity Laboratories, Inc.

John Abravanel Berdugo
CEO & Founder
US Longevity Laboratories, Inc. · U.S. Cannabis Laboratories, Inc.
Studying anti-aging properties within cannabis. Lab founder & contractor of record.

John Abravanel Berdugo
US Longevity Laboratories, Inc.
U.S. Cannabis Laboratories, Inc.
Studying anti-aging properties within cannabis. Laboratory founder & contractor of record.

Real science, real testing, real formulation — the research infrastructure of US Longevity Laboratories, applied to anti-aging, cellular health, and physician-led hormone and peptide care.
Enter the Laboratory
AI application development, deep-thinking SaaS tools, and applied research systems built by our Israel.com.AI team — the same AI infrastructure now being pointed directly at longevity science.
Enter the Intelligence
Every formulation, protocol, and recommendation on this platform traces back to real testing and real formulation science at US Longevity Laboratories in Beverly Hills — not a marketing team working backward from a bottle.
See Our LabEvery protocol developed under direct scientific oversight.
The same instrumentation used in clinical and forensic science, applied to longevity.
Hormone and peptide protocols directed by licensed, independently practicing physicians — never sold as an unsupervised bottle.
Your intake data, biomarkers, and goals shape your protocol, not a generic stack.
Proprietary tools built for longevity research and care, not repurposed generic software.
Part of a broader AI application and development platform, applied here to health and longevity.
Longevity.com.AI is powered by the same applied-AI team behind Israel.com.AI — building deep-thinking SaaS tools, AI applications, and data systems now focused specifically on anti-aging and longevity science: biomarker analysis, protocol personalization, and research acceleration.
See Our AI Work
Peptides, NAD+ & the Future of Cellular Health
An AI laboratory where longevity research and development meets artificial intelligence — engineered with US Longevity Laboratories, Inc., with AI specialty by Israel.com.AI.
INNOVATION • PERFORMANCE • LONGEVITY
Educational content, not medical advice. Peptide, NAD+, and hormone-related protocols require evaluation and prescription by a licensed physician. Supplement statements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease.

Tenured Professor of Genetics — Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School
About Harvard University
Founded in 1636 in Cambridge, Massachusetts, Harvard University is the oldest institution of higher learning in the United States and one of the world's foremost research universities. Its motto Veritas — truth — anchors a centuries-long tradition of scientific discovery, and Harvard Medical School remains a global epicenter for aging and geroscience research.
Dr. Sinclair's laboratory at the Paul F. Glenn Center investigates why we age and how to slow its effects. His team has produced landmark work on sirtuins and NAD+, the healthspan effects of resveratrol and NMN, and the Information Theory of Aging — the idea that aging is a reversible loss of epigenetic information, not accumulated damage.
Epigenetic Reprogramming
Reversing cellular age using Yamanaka factors.
NAD+ & NMN
Restoring cellular energy and metabolic health.
Sirtuins & Resveratrol
STACs that activate longevity pathways.
Disclaimer
This section is for informational purposes only. Longevity.com.AI and US Longevity Laboratories, Inc. are not in any way affiliated with, endorsed by, or working with Dr. David Sinclair or Harvard University at this time. We are currently working on reaching out to him to explore a potential collaboration.
Three decades of peer-reviewed work from the Paul F. Glenn Center for Biology of Aging Research — organized into the breakthroughs and publications that reframed aging as a treatable, reversible condition.
Landmark Breakthroughs
Cell
The Information Theory of Aging: DNA breaks cause epigenetic drift, cells lose their identity, and aging is a reversible loss of information — not damage accumulation.
Nature
Using three Yamanaka factors (OCT4, SOX2, KLF4) to reset the epigenetic age of retinal ganglion cells — restoring youthful vision in old mice without tumors.
Cell Metabolism
Long-term nicotinamide mononucleotide (NMN) supplementation restored NAD+ levels, improving muscle function, insulin sensitivity, and endurance in aged mice.
Nature
Resveratrol — a SIRT1 sirtuin-activating compound (STAC) — improved survival and organ health of mice on a high-calorie diet, launching the STAC drug program (Sirtris).
Selected Publications
Loss of epigenetic information as a cause of mammalian aging and reversal of the aging clock
CellReprogramming to recover youthful epigenetic information and restore vision
NatureA molecular map of the aging human retina
Nature CommunicationsIn vivo amelioration of age-related hallmarks by partial reprogramming of cells
CellLong-term administration of nicotinamide mononucleotide mitigates age-related physiological decline in mice
Cell MetabolismResveratrol improves health and survival of mice on a high-calorie diet
NatureSmall molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
NatureExtrachromosomal rDNA circles — a cause of aging in yeast
Cell
For military veterans and first responders. Physician-led testosterone and peptide optimization built around operational stress, shift work, and duty-related hormone decline.
Enter 613 Tactical
Recovery and resilience support for anyone living hard and moving fast — nutrient replenishment, sleep, and cellular recovery support for a demanding, high-output lifestyle.
Enter RestoreExpanding into dedicated protocols for fathers, mothers, healthy aging, and performance/preventative maintenance — each grounded in the same lab science, personalized by our AI systems, and delivered through the same physician network.
Every clinical protocol on Longevity.com.AI — including hormone optimization and peptide therapy — is directed by a licensed, independently practicing physician. Nothing here is a bottle shipped without a diagnosis behind it.
Meet Our Medical TeamAging is not one process — it is eighteen interconnected biological systems. Our research and protocols are organized around each.
NMN, NR, and mitochondrial fuel pathways
Physician-guided hormone health and vitality
Clearing aged "zombie" cells
The cell's energy engine
Targeted repair, recovery, and signaling peptides
Memory, focus, neuroprotection
Vascular health and circulatory resilience
Stem cell science, joint and tissue repair
The gut-longevity connection
NAD+ precursor studied for cellular energy support.
NAD+ PrecursorsAlternative NAD+ precursor pathway.
PolyphenolsPolyphenol studied alongside sirtuin activation research.
PolyphenolsStudied for autophagy support.
PolyphenolsFlavonoids studied in senolytic research.
NAD+ PrecursorsMethylation support, often paired with NMN.
Fat-Soluble VitaminsBone, immune, and cardiovascular support.
MineralsNervous system and sleep support.
A physician-formulated collection of face creams and serums engineered around cellular longevity — peptides, retinoids, and antioxidants at clinical concentration, presented in a dedicated clinical kiosk experience.

Longevity Skincare · Face Collection
Lab-Formulated
Developed alongside US Longevity Laboratories research.
Clinical Actives
Peptide & antioxidant concentrations at efficacious levels.
Physician-Reviewed
Every formula reviewed under clinical supervision.
Retinaldehyde · Bakuchiol
Argireline · Matrixyl 3002
Type I Collagen · Ceramides
Niacinamide · Vitamin C
Hyaluronic Acid · Panthenol
Encapsulated Retinol · Peptides

Clinical Concentration
Actives engineered at efficacious, laboratory-grade levels.
In collaboration with US Longevity Laboratories, Inc.
A physician-formulated collection of face creams and serums engineered around cellular longevity — peptides, retinoids, and antioxidants at clinical concentration.
Lab-Formulated
Developed alongside US Longevity Laboratories research.
Clinical Actives
Peptide and antioxidant concentrations at efficacious levels.
Barrier-First
Every formula supports the skin's structural integrity.
Overnight barrier repair engineered to support dermal collagen synthesis and cellular turnover.
Retinaldehyde · Bakuchiol · Squalane
Targeted peptide complex studied for visible firming and micro-circulation around the orbital rim.
Argireline · Matrixyl 3002 · Caffeine
Reinforces the moisture barrier with clinical-grade collagen peptides and lipid ceramides.
Type I Collagen · Ceramides · Niacinamide
Antioxidant serum formulated to support cellular energy pathways and even tone.
Niacinamide · Vitamin C (15%) · Glutathione
Multi-weight hyaluronic matrix for sustained dermal hydration and barrier resilience.
Hyaluronic Acid · Panthenol · Bisabolol
Time-release retinol engineered to minimize irritation while supporting renewal.
Encapsulated Retinol (0.5%) · Peptides · Vitamin E
Every formula is reviewed under physician supervision and produced to laboratory-grade standards.
Shop the CollectionGovernments and private capital are pouring billions into healthy-aging science. Explore the hubs leading the charge.
Dubai & Abu Dhabi
Singapore
Zurich & the Swiss Alps
Boston / Cambridge & the Bay Area
Tokyo & Kyoto
Luxury Longevity Destinations

We're mapping and planning a network of resort-style longevity rehabilitation centers — immersive destinations where diagnostics, therapies, nutrition, recovery, and the full US Longevity Laboratories protocol library live under one roof.
Inquire About Future LocationsDiagnostics on arrival
Personalized protocol design
On-site therapies (IV, peptide, regenerative)
Culinary longevity nutrition
Recovery & sleep suites
Continued care post-stay
Longevity hoodies, structured caps, and canvas totes — alongside dedicated shelves for 613 Tactical apparel, Restore products, and our longevity skincare and vitamin lines.
Visit the Store
A curated feed reporting only on longevity, anti-aging, and AI-driven healthspan science — including a dedicated dossier on Dr. David Sinclair of Harvard University.
A roundup of leading longevity biotech companies — including Altos Labs, Cambrian Bio, Junevity and BioAge Labs — advancing cellular reprogramming, senolytics and AI-driven drug discovery.
United StatesDubaiHis Highness Sheikh Mohammed bin Rashid issued Law No. 17 of 2026 establishing the Dubai Longevity Authority (DLA), a dedicated regulator to position the emirate as a global hub for longevity, wellness and advanced health.
Dubai, UAEAI & GeroscienceThe first cellular-reprogramming treatment aimed at reversing aging was administered to a human patient — a milestone for the reprogramming frontier of longevity science.
United StatesAI & GeroscienceA synthesis from the Aging Research and Drug Discovery meeting — led by Insilico Medicine (Abu Dhabi) and the University of Copenhagen — on how AI identifies precise aging biomarkers, builds 'aging clocks,' and accelerates drugs targeting primary aging drivers.
Abu Dhabi & CopenhagenJoin our research desk. We aggregate and share the latest breakthroughs in AI-driven longevity science — from NAD+ and peptide protocols to geroscience and clinical trials — straight to your inbox.
RESEARCH • PROTOCOLS • BREAKTHROUGHS
By subscribing you agree to receive research updates from Longevity.com.AI. We never share your email. Educational content only — not medical advice.
Speak with our team about diagnostics, protocols, and the science of living longer.
Compliance
Content on this site is educational and not medical advice. Hormone therapy (TRT), peptide therapy, and prescription-adjacent protocols require evaluation by a licensed physician. Supplement statements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease.